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ATH-1105 a Phase 1, Double-Blind, Placebo-Controlled, Single-and-Multiple-Oral-Dose, Safety, Tolerability, and Pharmacokinetic Study in Healthy Male and Female Subjects

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Trial Profile

ATH-1105 a Phase 1, Double-Blind, Placebo-Controlled, Single-and-Multiple-Oral-Dose, Safety, Tolerability, and Pharmacokinetic Study in Healthy Male and Female Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Feb 2026

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At a glance

  • Drugs ATH 1105 (Primary)
  • Indications Amyotrophic lateral sclerosis; Frontotemporal dementia
  • Focus Adverse reactions; First in man
  • Sponsors Athira Pharma; LeonaBio

Most Recent Events

  • 09 Jan 2026 According to an Athira Pharma media release, Athira Pharma is now called LeonaBio.
  • 06 Nov 2025 According to an Athira Pharma media release, the company presented data from phase 1 clinical trial of ATH-1105 at the 4th Annual ALS Drug Development Summit.
  • 14 Aug 2025 According to an Athira Pharma media release, the company presented results from this phase 1 clinical trial of ATH-1105 in healthy volunteers at the ALS Nexus 2025 conference in Dallas, Texas.

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