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A Phase 1 double-blind, randomized, placebo-controlled, single-ascending dose clinical trial is designed to investigate the safety, tolerability, and pharmacokinetics of oral administration of AB-161 in healthy subjects

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Trial Profile

A Phase 1 double-blind, randomized, placebo-controlled, single-ascending dose clinical trial is designed to investigate the safety, tolerability, and pharmacokinetics of oral administration of AB-161 in healthy subjects

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 18 Sep 2023

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At a glance

  • Drugs AB 161 (Primary)
  • Indications Hepatitis B
  • Focus Adverse reactions

    • Most Recent Events

    • 11 Sep 2023 Status changed from recruiting to discontinued due to pre-clinical toxicology finding not related to peripheral neuropathy. There were no safety issues reported in the healthy subjects that received single doses of AB-161 in the Phase 1 clinical trial.
    • 16 Mar 2023 According to an Arbutus Biopharma media release, initial single-ascending dose data from this study are expected in the second half of 2023.
    • 16 Mar 2023 According to an Arbutus Biopharma media release, first patient has been dosed in this study

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