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An Open-label, Multicenter, Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Efficacy of BA3182, a Bispecific Epithelial Cell Adhesion Molecule (EpCAM)/CD3 Antibody, in Patients With Advanced Adenocarcinoma

Trial Profile

An Open-label, Multicenter, Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Efficacy of BA3182, a Bispecific Epithelial Cell Adhesion Molecule (EpCAM)/CD3 Antibody, in Patients With Advanced Adenocarcinoma

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 30 May 2025

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At a glance

  • Drugs BA-3182 (Primary)
  • Indications Adenocarcinoma
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors BioAtla

Most Recent Events

  • 06 May 2025 According to a BioAtla media release, preliminary results from this trial will be presented at the ESMO Gastrointestinal Cancers Congress, July 2 - 5, 2025.
  • 06 May 2025 According to a BioAtla media release, company has dosed first 3 patients at 300 mg.
  • 27 Mar 2025 According to a BioAtla media release, company is Currently dosing QW cohorts with priming dose and a 100 microgram ongoing treatment dose. Two of three patients have cleared this dose level and we anticipate dosing the 300 microgram cohort once the final patient clears the dose-limiting toxicity (DLT) period on April 8th.

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