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A 12-week, Phase 2 Open-label, Sequential Dose Cohort Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 Treatment in Participants With Congenital Adrenal Hyperplasia (TouCAHn)

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Trial Profile

A 12-week, Phase 2 Open-label, Sequential Dose Cohort Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 Treatment in Participants With Congenital Adrenal Hyperplasia (TouCAHn)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 Oct 2025

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At a glance

  • Drugs Atumelnant (Primary) ; Abiraterone acetate; Fludrocortisone; Hydrocortisone; Lidocaine; Methylprednisolone; Prednisone
  • Indications Congenital adrenal hyperplasia; Cushing syndrome
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TouCAHn
  • Sponsors Crinetics Pharmaceuticals

Most Recent Events

  • 10 Oct 2025 Last checked against ClinicalTrials.gov record.
  • 23 Sep 2025 Status changed from active, no longer recruiting to completed.
  • 07 Aug 2025 According to a Crinetics Pharmaceuticals media release, company continued progress on the global development program for atumelnant across multiple trials, including enrollment completion of Cohort 4 of the adult Phase 2 study with data expected early in 2026.

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