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Clinical Trial of CD40L-augmented Tumor Infiltrating Lymphocytes (CD40L TIL) for Patients With Oncogene-Driven Advanced Non-Small Cell Lung Cancer (NSCLC)

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Trial Profile

Clinical Trial of CD40L-augmented Tumor Infiltrating Lymphocytes (CD40L TIL) for Patients With Oncogene-Driven Advanced Non-Small Cell Lung Cancer (NSCLC)

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 03 Oct 2025

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At a glance

  • Drugs Nivolumab (Primary) ; Tumour infiltrating lymphocytes (Primary) ; Cyclophosphamide; Fludarabine; Interleukin-2
  • Indications Brain metastases; Non-small cell lung cancer
  • Focus Adverse reactions

Most Recent Events

  • 29 Aug 2025 Status changed from recruiting to active, no longer recruiting.
  • 04 Feb 2025 Planned End Date changed from 1 Jan 2027 to 22 Apr 2025.
  • 04 Feb 2025 Planned primary completion date changed from 1 Jan 2025 to 22 Apr 2025.

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