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An Open-label, Non-randomized, Multi-center Pivotal Phase 3 Study to Evaluate the Efficacy and Safety of PET Imaging With [18F]PI-2620 for the Detection of Tau Deposition When Compared to Post-mortem Histopathology (ADvance)

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Trial Profile

An Open-label, Non-randomized, Multi-center Pivotal Phase 3 Study to Evaluate the Efficacy and Safety of PET Imaging With [18F]PI-2620 for the Detection of Tau Deposition When Compared to Post-mortem Histopathology (ADvance)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 21 Jan 2026

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At a glance

  • Drugs PI 2620 (Primary)
  • Indications Alzheimer's disease
  • Focus Diagnostic use; Registrational
  • Acronyms ADvance
  • Sponsors Life Molecular Imaging

Most Recent Events

  • 07 Jan 2026 Planned End Date changed from 1 Mar 2026 to 1 Jun 2027.
  • 07 Jan 2026 Planned primary completion date changed from 1 Dec 2025 to 1 Jun 2027.
  • 20 Jan 2023 New trial record

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