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A Molecularly Driven Phase 1b Dose Escalation and Dose Expansion Study of the DNA-PK Inhibitor Peposertib (M3814) in Combination With the ATR Inhibitor M1774

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A Molecularly Driven Phase 1b Dose Escalation and Dose Expansion Study of the DNA-PK Inhibitor Peposertib (M3814) in Combination With the ATR Inhibitor M1774

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 07 Mar 2025

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At a glance

  • Drugs Peposertib (Primary) ; Tuvusertib (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions

    • Most Recent Events

    • 22 Aug 2024 Planned End Date changed from 31 Aug 2024 to 31 Aug 2026.
    • 22 Aug 2024 Planned primary completion date changed from 31 Aug 2024 to 31 Aug 2026.
    • 24 May 2024 Planned initiation date changed from 25 May 2024 to 23 Aug 2024.

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