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A Phase 1 Study of the Polymerase Theta Inhibitor Novobiocin in BRCA-Mutant and Other DNA Damage Repair-Deficient Solid Tumors

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Trial Profile

A Phase 1 Study of the Polymerase Theta Inhibitor Novobiocin in BRCA-Mutant and Other DNA Damage Repair-Deficient Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 11 Apr 2025

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At a glance

  • Drugs Novobiocin (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions

    • Most Recent Events

    • 02 Aug 2024 Planned End Date changed from 1 Aug 2026 to 1 Sep 2026.
    • 26 Jul 2024 Planned number of patients changed from 30 to 31.
    • 26 Jul 2024 Planned End Date changed from 31 May 2024 to 1 Aug 2026.

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