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A Phase 1, Open-label, Dose Escalation and Dose Expansion Study of CLN-978 in Patients With Relapsed/Refractory (R/R) B-cell Non-Hodgkin Lymphoma (B-NHL)

Trial Profile

A Phase 1, Open-label, Dose Escalation and Dose Expansion Study of CLN-978 in Patients With Relapsed/Refractory (R/R) B-cell Non-Hodgkin Lymphoma (B-NHL)

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 28 Feb 2025

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At a glance

  • Drugs CLN 978 (Primary)
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; First in man
  • Sponsors Cullinan Therapeutics
  • Most Recent Events

    • 15 May 2024 According to Cullinan Oncology media release, the company has discontinued enrollment in the B-NHL study and will pursue development of CLN-978 in autoimmune diseases, with SLE as the initial indication.
    • 15 May 2024 Status changed from active, no longer recruiting to discontinued.
    • 30 Apr 2024 Status changed from discontinued to active, no longer recruiting.

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