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NeoAdjuvant Dynamic Marker - Adjusted Personalized Therapy Comparing Trastuzumab-deruxtecan Versus Pacli-/Docetaxel+Carboplatin+Trastuzumab+Pertuzumab in HER2+ Early Breast Cancer

Trial Profile

NeoAdjuvant Dynamic Marker - Adjusted Personalized Therapy Comparing Trastuzumab-deruxtecan Versus Pacli-/Docetaxel+Carboplatin+Trastuzumab+Pertuzumab in HER2+ Early Breast Cancer

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 13 Feb 2025

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At a glance

  • Drugs Trastuzumab-deruxtecan (Primary) ; Carboplatin; Docetaxel; Paclitaxel; Pertuzumab; Trastuzumab
  • Indications Early breast cancer; HER2 positive breast cancer
  • Focus Therapeutic Use
  • Acronyms ADAPTHER2-IV; WSG-ADAPT-HER2-IV
  • Most Recent Events

    • 04 Jun 2024 Status changed to recruiting, according to Trial design presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 04 Jun 2024 According to Trial design presented at the 60th Annual Meeting of the American Society of Clinical Oncology, study start was in January 2024 (45 sites, enrollment period 24 months). Estimated trial duration of is 5.5 years.
    • 04 Jun 2024 Trial design presented at the 60th Annual Meeting of the American Society of Clinical Oncology

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