Trial Profile

A Randomized, Phase 2, Open Label Study Evaluating Subcutaneous Administration of Isatuximab in Combination With Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma (RRMM)

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 05 Jul 2025

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At a glance

Drugs Carfilzomib (Primary) ; Dexamethasone (Primary) ; Dexamethasone (Primary) ; Isatuximab (Primary)
Indications Multiple myeloma
Focus Therapeutic Use
Acronyms IZALCO
Sponsors Sanofi; Sanofi-Aventis Recherche & Developpement

24 Jun 2025 The protocol has been amended to addition in treatment arm and size and addition in pharmacokinetic primary endpoints
24 Jun 2025 Planned number of patients changed from 71 to 118.
24 Jun 2025 Planned End Date changed from 1 Mar 2027 to 12 May 2028.

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