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A Phase 2a, Double-blind, Placebo-controlled, Multi-center, Randomized Study Evaluating LSTA1 When Added to Standard of Care (SoC) Versus Standard of Care Alone in Subjects With Advanced Solid Tumors (BOLSTER)

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Trial Profile

A Phase 2a, Double-blind, Placebo-controlled, Multi-center, Randomized Study Evaluating LSTA1 When Added to Standard of Care (SoC) Versus Standard of Care Alone in Subjects With Advanced Solid Tumors (BOLSTER)

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 01 Jun 2026

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At a glance

  • Drugs Cerepetide (Primary) ; Cisplatin; Docetaxel; Durvalumab; Gemcitabine; Paclitaxel
  • Indications Cholangiocarcinoma; Gallbladder cancer; Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oesophageal cancer; Oropharyngeal cancer; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions
  • Acronyms BOLSTER
  • Sponsors Lisata Therapeutics

Most Recent Events

  • 26 May 2026 The protocol has been amended to change in time frame for primary endpoint.
  • 26 May 2026 Status changed from active, no longer recruiting to discontinued.
  • 07 Aug 2025 According to a Lisata Therapeutics media release, company decided to stop enrollment at approximately 20 patients to accelerate data readout and optimize capital allocation in the second-line CCA cohort .

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