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A Phase 1 Study of Peposertib (M3814) and Low-Dose Liposomal Doxorubicin (Doxil) in Patients With Metastatic Leiomyosarcoma and Other Soft Tissue Sarcomas

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Trial Profile

A Phase 1 Study of Peposertib (M3814) and Low-Dose Liposomal Doxorubicin (Doxil) in Patients With Metastatic Leiomyosarcoma and Other Soft Tissue Sarcomas

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 11 Jun 2025

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At a glance

  • Drugs Doxorubicin liposomal (Primary) ; Peposertib (Primary)
  • Indications Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Malignant fibrous histiocytoma; Sarcoma; Soft tissue sarcoma; Synovial sarcoma
  • Focus Adverse reactions

Most Recent Events

  • 05 Jun 2025 Planned End Date changed from 3 May 2025 to 3 May 2026.
  • 05 Jun 2025 Planned primary completion date changed from 3 May 2025 to 3 May 2026.
  • 18 Mar 2025 Planned number of patients changed from 36 to 30.

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