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A Phase 1 Study of Peposertib (M3814) and Low-Dose Liposomal Doxorubicin (Doxil) in Patients With Metastatic Leiomyosarcoma and Other Soft Tissue Sarcomas

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A Phase 1 Study of Peposertib (M3814) and Low-Dose Liposomal Doxorubicin (Doxil) in Patients With Metastatic Leiomyosarcoma and Other Soft Tissue Sarcomas

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 22 Mar 2025

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At a glance

  • Drugs Doxorubicin liposomal (Primary) ; Peposertib (Primary)
  • Indications Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Malignant fibrous histiocytoma; Sarcoma; Soft tissue sarcoma; Synovial sarcoma
  • Focus Adverse reactions

    • Most Recent Events

    • 01 Feb 2024 Planned initiation date (estimated date of first participant enrollment) changed from 2 Feb 2024 to 2 May 2024.
    • 19 Dec 2023 Planned initiation date (estimated date of first participant enrollment) changed from 24 Feb 2023 to 2 Feb 2024.
    • 19 Dec 2023 Status changed from suspended to recruiting.

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