Trial Profile

A Phase I Clinical Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-Malignancy Activity of AC676 in Patients With Relapsed/Refractory B-cell Malignancies

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 14 Oct 2025

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At a glance

Drugs AC-0676 (Primary)
Indications B-cell lymphoma; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Waldenstrom's macroglobulinaemia
Focus Adverse reactions; First in man
Sponsors Accutar Biotechnology

02 Oct 2025 Planned End Date changed from 1 Dec 2025 to 31 Mar 2026.
02 Oct 2025 Planned primary completion date changed from 1 Jul 2025 to 31 Mar 2026.
10 Dec 2024 Study design were presented at the 66th American Society of Hematology Annual Meeting and Exposition.

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