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Randomized, Double-blind, Placebo-controlled Proof-of-Concept (PoC) Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)

Trial Profile

Randomized, Double-blind, Placebo-controlled Proof-of-Concept (PoC) Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 10 Jun 2025

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At a glance

  • Drugs Efzofitimod (Primary)
  • Indications Interstitial lung diseases; Systemic scleroderma
  • Focus Proof of concept; Therapeutic Use
  • Acronyms EFZO-CONNECT
  • Sponsors aTyr Pharma

Most Recent Events

  • 04 Jun 2025 Interim results presented in an aTyr pharma Media Release.
  • 07 May 2025 According to an aTyr pharma media release, Interim data will focus on skin assessments measured at baseline and week 12 in approximately eight patients, including patients in both the efzofitimod and placebo arms.
  • 07 May 2025 Planned End Date changed from 1 Dec 2024 to 1 Apr 2026.

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