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A Phase 2 Study of Preoperative Pembrolizumab and Chemotherapy Followed by Adjuvant Pembrolizumab in Resectable Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma

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Trial Profile

A Phase 2 Study of Preoperative Pembrolizumab and Chemotherapy Followed by Adjuvant Pembrolizumab in Resectable Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 27 Jun 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Docetaxel (Primary) ; Pembrolizumab (Primary)
  • Indications Head and neck cancer; Squamous cell cancer
  • Focus Therapeutic Use

Most Recent Events

  • 22 Jun 2025 Planned primary completion date changed from 20 May 2025 to 31 Dec 2027.
  • 03 Oct 2023 Planned End Date changed from 20 Feb 2030 to 20 May 2030.
  • 03 Oct 2023 Planned primary completion date changed from 20 Feb 2025 to 20 May 2025.

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