An Open-Label, Multiple-Ascending Dose Study to Assess the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Different Dose Levels of Povetacicept in Subjects With Autoantibody-Associated Glomerular Diseases (RUBY-3)
Latest Information Update: 24 Jun 2025
At a glance
- Drugs Povetacicept (Primary)
- Indications IgA nephropathy; Lupus nephritis; Membranous glomerulonephritis
- Focus Adverse reactions
- Acronyms RUBY-3
- Sponsors Alpine Immune Sciences
Most Recent Events
- 15 Jun 2025 Status changed from recruiting to active, no longer recruiting.
- 05 May 2025 According to a vertex pharma media release, Vertex expects to share next steps from other RUBY-3 study later this year.
- 05 May 2025 According to a vertex pharma media release, Vertex plans to present updated data from the IgAN and pMN cohorts of the RUBY-3 study at upcoming medical congresses