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Phase II Open-Label Multi-Cohort Study Evaluating CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Patients With Advanced Chemorefractory Colorectal, Pancreatic, or Other Solid Cancers

Trial Profile

Phase II Open-Label Multi-Cohort Study Evaluating CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Patients With Advanced Chemorefractory Colorectal, Pancreatic, or Other Solid Cancers

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 06 Jun 2025

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At a glance

  • Drugs Devimistat (Primary) ; Fluorouracil (Primary) ; Gemcitabine (Primary) ; Hydroxychloroquine (Primary)
  • Indications Adenocarcinoma; Biliary cancer; Colorectal cancer; Gastric cancer; Non-small cell lung cancer; Oesophageal cancer; Ovarian cancer; Pancreatic cancer; Solid tumours; Urogenital cancer
  • Focus Therapeutic Use

Most Recent Events

  • 30 Apr 2025 Results(n=26) presented at the 116th Annual Meeting of the American Association for Cancer Research
  • 08 Mar 2023 Status changed from not yet recruiting to recruiting.
  • 20 Feb 2023 New trial record

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