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Phase 3, Interventional, Multicentre, Open-label, Randomized Study Comparing Rituximab Plus Zanubrutinib to Rituximab Monotherapy in Previously Untreated, Symptomatic Splenic Marginal Zone Lymphoma (RITZ)

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Trial Profile

Phase 3, Interventional, Multicentre, Open-label, Randomized Study Comparing Rituximab Plus Zanubrutinib to Rituximab Monotherapy in Previously Untreated, Symptomatic Splenic Marginal Zone Lymphoma (RITZ)

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 16 Aug 2025

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At a glance

  • Drugs Rituximab (Primary) ; Zanubrutinib (Primary)
  • Indications Marginal zone B-cell lymphoma
  • Focus Therapeutic Use
  • Acronyms RITZ

Most Recent Events

  • 17 May 2024 Planned End Date changed from 1 Feb 2029 to 1 May 2029.
  • 17 May 2024 Planned primary completion date changed from 1 Feb 2029 to 1 May 2029.
  • 20 Oct 2023 Planned End Date changed from 1 Sep 2028 to 1 Feb 2029.

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