Trial Profile

Phase Ib Dose Finding Study Assessing Safety and Activity of [177Lu]Lu-NeoB in Combination With Radiotherapy and Temozolomide in Subjects With Newly Diagnosed Glioblastoma With MGMT Methylated or Unmethylated Promoter Status

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 06 Jul 2026

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At a glance

Drugs Gallium 68 NeoBOMB1 (Primary) ; Lutetium-177 NeoBOMB1 (Primary) ; Temozolomide
Indications Glioblastoma
Focus Adverse reactions
Sponsors Novartis; Novartis Pharmaceuticals

14 May 2026 Planned End Date changed from 1 Jul 2032 to 8 Nov 2028.
14 May 2026 Planned primary completion date changed from 10 Dec 2026 to 8 Nov 2028.
02 Feb 2026 Status changed from recruiting to active, no longer recruiting.

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