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An Open-Label, Single-Arm, Phase II Study of Pembrolizumab, Plinabulin Plus Etoposide and Platinum as First-Line Therapy for Extensive-Stage Small-Cell Lung Cancer

Trial Profile

An Open-Label, Single-Arm, Phase II Study of Pembrolizumab, Plinabulin Plus Etoposide and Platinum as First-Line Therapy for Extensive-Stage Small-Cell Lung Cancer

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 31 Mar 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Etoposide (Primary) ; Pembrolizumab (Primary) ; Plinabulin (Primary)
  • Indications Small cell lung cancer
  • Focus Proof of concept; Therapeutic Use

Most Recent Events

  • 27 Mar 2025 According to a BeyondSpring Pharmaceuticals media release, Preliminary data from Phase 2 of Study 302 in 1L ES-SCLC is expected in second half of 2025.
  • 11 Feb 2025 Planned primary completion date changed from 1 May 2025 to 1 Jun 2025.
  • 25 Mar 2024 According to a BeyondSpring Pharmaceuticals media release, first patient has been dosed in this trial. This trial is being conducted in the Wuhan Union Hospital in China, with Dr. Xiaorong Dong as principal investigator.

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