Trial Profile

SMART (Smallpox Vaccine for Mpox Post-Exposure Prophylaxis: A Cluster Randomized Controlled Trial)

Status: Recruiting

Phase of Trial: Phase IV

Latest Information Update: 16 Jul 2025

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At a glance

Drugs Modified vaccinia Ankara (Primary) ; Typhoid vaccine Vi-polysaccharide
Indications Monkeypox
Focus Therapeutic Use
Acronyms SMART

Most Recent Events

06 Jul 2025 Planned number of patients changed from 1560 to 3000.
06 Jul 2025 Planned End Date changed from 1 Dec 2025 to 1 Dec 2026.
06 Jul 2025 Planned primary completion date changed from 1 Jun 2025 to 1 Jun 2026.

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