Trial Profile

SMART (Smallpox Vaccine for Mpox Post-Exposure Prophylaxis: A Cluster Randomized Controlled Trial)

Status: Active, no longer recruiting

Phase of Trial: Phase IV

Latest Information Update: 19 Aug 2026

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At a glance

Drugs Modified vaccinia Ankara (Primary) ; Typhoid vaccine Vi-polysaccharide
Indications Monkeypox
Focus Therapeutic Use
Acronyms SMART

Most Recent Events

12 Aug 2026 Planned End Date changed from 1 Dec 2026 to 20 Oct 2026.
12 Aug 2026 Status changed from recruiting to active, no longer recruiting.
06 Jul 2025 Planned number of patients changed from 1560 to 3000.

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