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A Phase 3, Double-Blind, Randomized, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Prurigo Nodularis

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A Phase 3, Double-Blind, Randomized, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Prurigo Nodularis

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 24 Mar 2025

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At a glance

  • Drugs Ruxolitinib (Primary)
  • Indications Prurigo nodularis
  • Focus Therapeutic Use
  • Acronyms TRuE-PN1
  • Sponsors Incyte Corporation

    • Most Recent Events

    • 08 Mar 2025 According to Incyte Corporation media release, the findings from the TRuE-PN1 and TRuE-PN2 studies will inform planned discussions with regulatory authorities to find out the next steps.
    • 08 Mar 2025 According to an Incyte Corporation media release, full positive data from this study, showing that the study met all primary and key secondary endpoints, was presented in a late-breaking oral presentation, at 2025 American Academy of Dermatology Annual Meeting being held March 7-11, 2025, in Orlando during Session: S028 - Late-Breaking Research: Session 1.
    • 08 Mar 2025 According to an Incyte Corporation media release, primary endpoint (Worst-Itch Numeric Rating Scale (WI-NRS) 4-point improvement in WI-NRS score Response) has been met.

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