Trial Profile

Quadruple Immunotherapy for Paediatric Patients With Relapsed or Refractory Neuroblastoma

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 08 Oct 2025

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At a glance

Drugs Aldesleukin (Primary) ; Dinutuximab beta (Primary) ; Naxitamab (Primary) ; Sargramostim (Primary) ; Spironolactone (Primary)
Indications Neuroblastoma
Focus Therapeutic Use

Most Recent Events

15 Sep 2025 Planned primary completion date changed from 31 Dec 2024 to 31 Dec 2025.
04 Mar 2024 Anti-GD2 antibody (Naxitamab) can be used as an alternative instead of dinutuximab, to be given on day -5, day -3, day +1 and day +3
09 Mar 2023 New trial record

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