A Randomized, Crossover, Double Blind, Placebo Controlled, Phase 2 Study to Evaluate the Efficacy and Safety of Lorundrostat in Addition to Sodium-Glucose Cotransporter-2 Inhibitors, in Adults with Hypertension and Chronic Kidney Disease with Albuminuria

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 26 Feb 2025

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At a glance

Drugs Lorundrostat (Primary) ; Dapagliflozin
Indications Hypertension; Resistant hypertension
Focus Adverse reactions; Proof of concept; Therapeutic Use
Acronyms Explore-CKD
Sponsors Mineralys Therapeutics

Most Recent Events

21 Feb 2025 Planned primary completion date changed from 1 Feb 2025 to 1 May 2025.
21 Feb 2025 Status changed from recruiting to active, no longer recruiting.
21 Nov 2024 Planned End Date changed from 1 Jan 2025 to 1 May 2025.

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