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A Phase 3, Double-Blind, Randomized, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Prurigo Nodularis

Trial Profile

A Phase 3, Double-Blind, Randomized, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Prurigo Nodularis

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 07 May 2025

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At a glance

  • Drugs Ruxolitinib (Primary)
  • Indications Prurigo nodularis
  • Focus Therapeutic Use
  • Acronyms TRuE-PN2
  • Sponsors Incyte Corporation

Most Recent Events

  • 08 Mar 2025 Primary endpoint has not been met. (Worst-Itch Numeric Rating Scale (WI-NRS) 4-point improvement in WI-NRS score Response), According to Incyte Corporation media release.
  • 08 Mar 2025 Results presented in the Incyte Corporation Media Release.
  • 08 Mar 2025 According to Incyte Corporation media release, the findings from the TRuE-PN1 and TRuE-PN2 studies will inform planned discussions with regulatory authorities to find out the next steps.

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