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A Cancer Research UK Phase I/II trial to assess the safety, tolerability, pharmacokinetics and preliminary anti-tumour activity of UCB4594 alone and in combination with anti-cancer treatments in participants with advanced malignancies

Trial Profile

A Cancer Research UK Phase I/II trial to assess the safety, tolerability, pharmacokinetics and preliminary anti-tumour activity of UCB4594 alone and in combination with anti-cancer treatments in participants with advanced malignancies

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 23 Aug 2024

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At a glance

  • Drugs UCB-4594 (Primary)
  • Indications Advanced breast cancer; Carcinoma; Cervical cancer; Colorectal cancer; Gastric cancer; Head and neck cancer; Non-small cell lung cancer; Oesophageal cancer; Ovarian cancer; Pancreatic cancer; Renal cancer; Solid tumours; Squamous cell cancer; Triple negative breast cancer
  • Focus Adverse reactions; First in man

Most Recent Events

  • 05 Apr 2024 Status changed from not yet recruiting to recruiting.
  • 07 Feb 2024 Planned initiation date changed from 16 Feb 2024 to 13 Mar 2024.
  • 24 Jan 2024 Recruitment completion is expected on 1 Nov 2028, according to ISRCTN: Current Controlled Trials.

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