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A Randomized, Double-Blind, Placebo Controlled, Parallel Arm, Multicenter, Phase 2 Study to Evaluate the Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled Hypertension on a Standardized Medication Regimen

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Trial Profile

A Randomized, Double-Blind, Placebo Controlled, Parallel Arm, Multicenter, Phase 2 Study to Evaluate the Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled Hypertension on a Standardized Medication Regimen

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 28 Apr 2025

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At a glance

  • Drugs Lorundrostat (Primary)
  • Indications Hypertension; Resistant hypertension
  • Focus Registrational; Therapeutic Use
  • Acronyms ADVANCE-HTN
  • Sponsors Mineralys Therapeutics

Most Recent Events

  • 23 Apr 2025 According to a Mineralys Therapeutics media release,the New England Journal of Medicine (NEJM) published the detailed results from the \pivotal Phase 2 Advance-HTN trial,
  • 23 Apr 2025 Results presented in a Mineralys Therapeutics media release.
  • 29 Mar 2025 According to a Mineralys Therapeutics media release, the detailed results from Advance-HTN were presented in a late-breaking session at the American College of Cardiology's Annual Scientific Session & Expo (ACC.25) on Saturday, March 29, 2025, at 1:30 p.m. CT.

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