A Randomized, Parallel-group, Double-blind, Placebo-controlled, Multicenter Phase III Trial to Evaluate Efficacy and Safety of Secukinumab Administered Subcutaneously Versus Placebo, in Combination With a Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 08 Mar 2025

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At a glance

Drugs Prednisone (Primary) ; Secukinumab (Primary)
Indications Polymyalgia rheumatica
Focus Registrational; Therapeutic Use
Acronyms REPLENISH
Sponsors Novartis Pharmaceuticals

Most Recent Events

05 Sep 2024 Status changed from recruiting to active, no longer recruiting.
14 Mar 2024 Planned End Date changed from 22 Dec 2025 to 17 Feb 2026.
14 Mar 2024 Planned primary completion date changed from 7 Jul 2025 to 2 Sep 2025.

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