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An Open-Label Extension Study to Assess the Long-Term Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Hypertension

Trial Profile

An Open-Label Extension Study to Assess the Long-Term Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Hypertension

Status: Recruiting
Phase of Trial: Phase II/III

Latest Information Update: 26 Mar 2025

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At a glance

  • Drugs Lorundrostat (Primary)
  • Indications Hypertension; Resistant hypertension
  • Focus Therapeutic Use
  • Acronyms Transform-HTN
  • Sponsors Mineralys Therapeutics

Most Recent Events

  • 25 Mar 2025 According to a Mineralys Therapeutics media release, the company announced it will host a conference call and webinar featuring Dr. Luke Laffin of the Cleveland Clinic, who will discuss the latest results from the pivotal Advance-HTN and Launch-HTN clinical trials and offer his perspective on the unmet medical need in uncontrolled hypertension (uHTN) or resistant hypertension (rHTN) and the potential of lorundsrostat to change the current treatment paradigm on Tuesday, April 1st, @ 8:00 a.m.
  • 23 Jul 2024 Planned number of patients changed from 900 to 1400.
  • 23 Jul 2024 Planned End Date changed from 1 Dec 2025 to 1 Dec 2026.

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