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A Phase 2b, Prospective, Multicenter, Randomized, Double-Masked, Active-Controlled Study to Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With Diabetic Macular Edema

Trial Profile

A Phase 2b, Prospective, Multicenter, Randomized, Double-Masked, Active-Controlled Study to Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With Diabetic Macular Edema

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 May 2025

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At a glance

  • Drugs Foselutoclax (Primary) ; Aflibercept
  • Indications Diabetic macular oedema
  • Focus Registrational; Therapeutic Use
  • Acronyms ASPIRE
  • Sponsors UNITY Biotechnology

Most Recent Events

  • 14 May 2025 Status changed from active, no longer recruiting to completed.
  • 05 May 2025 Results presented full 36-week results in UNITY Biotechnology media release
  • 01 May 2025 According to UNITY Biotechnology media release, data from this trial will be presented at the Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting

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