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A Phase 1/2 Study of CB-103 (Oral Pan-NOTCH Inhibitor) With Abemaciclib or Lenvatinib in Combination in Patients With NOTCH Activated Adenoid Cystic Carcinoma (CALCulus)

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Trial Profile

A Phase 1/2 Study of CB-103 (Oral Pan-NOTCH Inhibitor) With Abemaciclib or Lenvatinib in Combination in Patients With NOTCH Activated Adenoid Cystic Carcinoma (CALCulus)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 24 Jun 2025

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At a glance

Most Recent Events

  • 17 Jun 2025 Planned number of patients changed from 34 to 32.
  • 17 Jun 2025 Status changed from active, no longer recruiting to recruiting.
  • 17 Jun 2025 Planned End Date changed from 1 Jun 2026 to 1 Jun 2027.

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