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Efficacy and Safety of 72-hour Infusion of Prostacyclin (1 ng/kg/Min) in Mechanically Ventilated Patients With Infectious Pulmonary Endotheliopathy - a Multicenter Randomized, Placebo-controlled, Blinded, Investigator-initiated Trial

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Trial Profile

Efficacy and Safety of 72-hour Infusion of Prostacyclin (1 ng/kg/Min) in Mechanically Ventilated Patients With Infectious Pulmonary Endotheliopathy - a Multicenter Randomized, Placebo-controlled, Blinded, Investigator-initiated Trial

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 25 Sep 2025

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At a glance

  • Drugs Iloprost (Primary)
  • Indications Respiratory insufficiency
  • Focus Therapeutic Use
  • Acronyms COMBAT-ARF

Most Recent Events

  • 22 Aug 2025 Planned End Date changed from 30 Dec 2026 to 30 Sep 2027.
  • 22 Aug 2025 Planned primary completion date changed from 30 Dec 2026 to 30 Sep 2027.
  • 15 Feb 2024 Planned End Date changed from 20 Mar 2025 to 20 Sep 2025.

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