A multicenter, randomized, placebo-controlled, double-blind, parallel-group study, to assess efficacy, safety and immunogenicity of JNJ-64042056, a phosphorylated tau targeted active immunotherapy, in participants with preclinical Alzheimer's disease
Latest Information Update: 20 Feb 2026
At a glance
- Drugs ACI 35.030 (Primary)
- Indications Alzheimer's disease
- Focus Registrational; Therapeutic Use
- Acronyms ReTain
- Sponsors AC Immune; Janssen-Cilag
Most Recent Events
- 17 Feb 2026 Status changed from recruiting to active, no longer recruiting.
- 16 Jan 2026 Planned primary completion date changed from 17 Jul 2031 to 16 Jul 2032.
- 22 Jun 2025 Planned End Date changed from 31 May 2033 to 7 Jul 2034.