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A Phase Ib/II, Two-part, Non-randomized, Open-label Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetics of Chidamide in Combination With Regorafenib in Patients With Hepatocellular Carcinoma

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Trial Profile

A Phase Ib/II, Two-part, Non-randomized, Open-label Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetics of Chidamide in Combination With Regorafenib in Patients With Hepatocellular Carcinoma

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 14 Mar 2025

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At a glance

  • Drugs Regorafenib (Primary) ; Tucidinostat (Primary)
  • Indications Liver cancer
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
  • Sponsors GNT Biotech and Medicals Corporation

Most Recent Events

  • 12 Mar 2025 Status changed from recruiting to discontinued.
  • 22 Feb 2024 The protocol has been amended, the study will now recruit patients who are 18 years of age or older.
  • 24 Mar 2023 New trial record

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