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A PHASE 2, RANDOMIZED, OPEN-LABEL STUDY OF ENCORAFENIB AND BINIMETINIB PLUS PEMBROLIZUMAB VERSUS NIVOLUMAB AND IPILIMUMAB IN PARTICIPANTS WITH BRAF V600E/K MUTATION-POSITIVE MELANOMA WHO PROGRESSED DURING OR AFTER PRIOR TREATMENT WITH ANTI-PD-1 THERAPY

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Trial Profile

A PHASE 2, RANDOMIZED, OPEN-LABEL STUDY OF ENCORAFENIB AND BINIMETINIB PLUS PEMBROLIZUMAB VERSUS NIVOLUMAB AND IPILIMUMAB IN PARTICIPANTS WITH BRAF V600E/K MUTATION-POSITIVE MELANOMA WHO PROGRESSED DURING OR AFTER PRIOR TREATMENT WITH ANTI-PD-1 THERAPY

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 12 Mar 2026

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At a glance

Most Recent Events

  • 09 Mar 2026 Status changed from active, no longer recruiting to discontinued.
  • 13 Jan 2026 Planned End Date changed from 31 Dec 2025 to 19 Jan 2026.
  • 18 Dec 2025 Planned primary completion date changed from 31 Dec 2025 to 19 Jan 2026.

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