Trial Profile

A Dose Escalation Phase I Trial of the Safety and Immunogenicity of RG1-VLP, A Candidate Broadly Protective Vaccine for the Prevention of HPV-Associated Cancer

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 03 Sep 2026

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At a glance

Drugs HPV16 RG1 VLP (Primary) ; Human Papillomavirus 9-valent recombinant vaccine Merck (Primary)
Indications Human papillomavirus infections
Focus Adverse reactions; First in man; Proof of concept

Most Recent Events

16 Jun 2026 Planned End Date changed from 1 Jun 2027 to 1 Aug 2028.
16 Jun 2026 Planned primary completion date changed from 1 Jun 2026 to 1 Feb 2028.
29 Sep 2025 Status changed from suspended to recruiting.

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