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Phase 2a clinical trial of psilocybin-assisted psychotherapy in the treatment of patients suffering from Irritable Bowel Syndrome (IBS) who experience chronic abdominal pain and other debilitating gastrointestinal symptoms

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Trial Profile

Phase 2a clinical trial of psilocybin-assisted psychotherapy in the treatment of patients suffering from Irritable Bowel Syndrome (IBS) who experience chronic abdominal pain and other debilitating gastrointestinal symptoms

Status: Planning
Phase of Trial: Phase II

Latest Information Update: 12 Jan 2024

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At a glance

  • Drugs Psilocybin (Primary)
  • Indications Abdominal pain
  • Focus Therapeutic Use

    • Most Recent Events

    • 08 Jan 2024 According to a Tryp Therapeutics media release, the company is preparing to initiate a Phase 2a clinical trial in collaboration with Massachusetts General Hospital for the treatment of abdominal pain and visceral tenderness in patients suffering from irritable bowel syndrome.
    • 08 Jan 2024 According to a Tryp Therapeutics media release, A Phase 2a, Open-label, Pilot Study to Assess the Safety and Efficacy of Oral Psilocybin (TRP-8802) Administration in Concert with Psychotherapy Among Adult Patients with Irritable Bowel Syndrome is nearing commencement with patient dosing expected in the first half of 2024.
    • 13 Jul 2023 According to a Tryp Therapeutics media release, company has received confirmation from the U.S. Food and Drug Administration ("FDA") that its review of Tryp's Investigational New Drug ("IND") #163,994 is complete and the Company may proceed with its Phase 2a clinical trial at Massachusetts General Hospital (MGH)

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