Trial Profile

An Open-Label Phase II Clinical Trial Assessing the Safety, Feasibility, Efficacy and Immunological Correlates of Heterologous Prime-Boost With pBI-11 (IM) and TA-HPV (IM) Combined With Pembrolizumab as Treatment for Patients With Advanced, PD-L1 CPS≥1, hrHPV+ Oropharyngeal Cancer

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 24 Jun 2024

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At a glance

Drugs DNA vaccines (Primary) ; Human papillomavirus vaccine (Primary) ; Pembrolizumab (Primary)
Indications Human papillomavirus infections; Oropharyngeal cancer
Focus Therapeutic Use

04 Jun 2024 Trial design presented at the 60th Annual Meeting of the American Society of Clinical Oncology.
12 Jul 2023 Planned End Date changed from 30 Apr 2028 to 30 Sep 2028.
12 Jul 2023 Planned primary completion date changed from 30 Apr 2027 to 30 Sep 2027.

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