Trial Profile

Phase I/II Study of Ladarixin and Sotorasib in Advanced KRAS G12C Mutant Non-Small Cell Lung Cancer (NSCLC)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 19 Jan 2026

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At a glance

Drugs Ladarixin (Primary) ; Sotorasib (Primary)
Indications Non-small cell lung cancer; Squamous cell cancer
Focus Adverse reactions; Therapeutic Use

Most Recent Events

30 Dec 2025 Planned End Date changed from 1 Aug 2026 to 1 Aug 2027.
30 Dec 2025 Planned primary completion date changed from 1 Aug 2025 to 1 Aug 2027.
07 Aug 2023 Phase of the trial is changed form phase 1 to phase 1/2. "Progression Free Survival (PFS)" is added as a primary end-point , thus making "TU" also a trial focus.

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