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A Phase 1 Dose-Escalation and Expansion Study to Assess Safety and Preliminary Antitumor Activity of Debio 0123 in Combination With Carboplatin and Etoposide in Adult Participants With Small Cell Lung Cancer That Recurred or Progressed After Previous Standard Platinum-Based Therapy

Trial Profile

A Phase 1 Dose-Escalation and Expansion Study to Assess Safety and Preliminary Antitumor Activity of Debio 0123 in Combination With Carboplatin and Etoposide in Adult Participants With Small Cell Lung Cancer That Recurred or Progressed After Previous Standard Platinum-Based Therapy

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 30 Nov 2024

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At a glance

  • Drugs Carboplatin (Primary) ; Debio 0123 (Primary) ; Etoposide (Primary)
  • Indications Small cell lung cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Debiopharm
  • Most Recent Events

    • 17 Sep 2024 Trial design presented at the 49th European Society for Medical Oncology Congress.
    • 23 May 2024 Planned number of patients changed from 54 to 78.
    • 30 May 2023 According to a Debiopharm media release, first patient dosed at Vall d'Hebron Hospital in this study.

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