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A Phase Ib/II Trial of Cadonilimab (PD-1/CTLA-4 Bispecific Antibody) in Combination With Anlotinib and Docetaxel in Patients (Pts) With Checkpoint Inhibitor (CPI)-Experienced Advanced Non-small Cell Lung Cancer (NSCLC)

Trial Profile

A Phase Ib/II Trial of Cadonilimab (PD-1/CTLA-4 Bispecific Antibody) in Combination With Anlotinib and Docetaxel in Patients (Pts) With Checkpoint Inhibitor (CPI)-Experienced Advanced Non-small Cell Lung Cancer (NSCLC)

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 11 Dec 2024

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At a glance

  • Drugs Cadonilimab (Primary) ; Catequentinib (Primary) ; Docetaxel (Primary)
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 04 Dec 2024 According to an Akeso, Inc media release, company announced results from this phase Ib/II clinical study (AK104-IIT-018) of cadonilimab in patients with advanced or metastatic non-small cell lung cancer (NSCLC) who had progressed after prior PD-(L)1 inhibitor treatment, were presented at the 2024 Asian Conference on Lung Cancer (ACLC).
  • 04 Dec 2024 According to an Akeso, Inc media release, as of May 31, 2024, 46 patients had been enrolled in the study.
  • 04 Dec 2024 Results presented in an Akeso, Inc media release

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