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A Phase 1, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Efficacy of DZD8586 in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (B-NHL)

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Trial Profile

A Phase 1, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Efficacy of DZD8586 in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (B-NHL)

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Jul 2024

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At a glance

  • Drugs DZD 8586 (Primary)
  • Indications B-cell lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Dizal Pharmaceutical

    • Most Recent Events

    • 23 Jul 2024 Planned number of patients changed from 20 to 230.
    • 23 Jul 2024 Status changed from not yet recruiting to recruiting.
    • 12 Dec 2023 Results of pooled analysis (As of June 15, 2023, n=17 from two studies NCT05844956 and NCT05824585) assessing safety, pharmacokinetics (PK), pharmacodynamics (PD) and anti-tumor efficacy of DZD8586 in Patients with B-Cell Non-Hodgkin Lymphoma presented at the 65th American Society of Hematology Annual Meeting and Exposition

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