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A Double-Masked, Randomized, Placebo-Controlled, Parallel-Group, 12-Week Administration With Two-Week Gradual Dose Taper Phase and 38-Week Follow-Up Phase, Phase 3 Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Simultaneous Cataract Surgery and Descemetorhexis in Subjects With Fuchs Endothelial Corneal Dystrophy

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A Double-Masked, Randomized, Placebo-Controlled, Parallel-Group, 12-Week Administration With Two-Week Gradual Dose Taper Phase and 38-Week Follow-Up Phase, Phase 3 Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Simultaneous Cataract Surgery and Descemetorhexis in Subjects With Fuchs Endothelial Corneal Dystrophy

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 06 Mar 2025

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At a glance

  • Drugs Ripasudil (Primary)
  • Indications Fuchs' endothelial dystrophy
  • Focus Therapeutic Use
  • Sponsors Kowa Research Institute

    • Most Recent Events

    • 01 Nov 2024 Status changed from recruiting to active, no longer recruiting.
    • 29 Oct 2024 Planned End Date changed from 1 Jan 2025 to 1 Oct 2025.
    • 29 Oct 2024 Planned primary completion date changed from 1 Jun 2024 to 1 Oct 2024.

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