Trial Profile

A Phase 1, Open-Label, Fixed-Sequence Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors Harboring ROS1 or NTRK1-3 Rearrangements

Status: Withdrawn prior to enrolment

Phase of Trial: Phase I

Latest Information Update: 04 Apr 2025

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At a glance

Drugs Digoxin (Primary) ; Metformin (Primary) ; Repotrectinib (Primary) ; Rosuvastatin (Primary)
Indications CNS cancer; Solid tumours
Focus Pharmacokinetics
Sponsors Turning Point Therapeutics

01 Apr 2025 Status changed from not yet recruiting to withdrawn prior to enrolment.
19 Jul 2024 Status changed from recruiting to not yet recruiting.
19 Jul 2023 Planned End Date changed from 1 Nov 2025 to 30 Nov 2025.

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