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A Phase 1, Open-Label, Fixed-Sequence Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors Harboring ROS1 or NTRK1-3 Rearrangements

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A Phase 1, Open-Label, Fixed-Sequence Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors Harboring ROS1 or NTRK1-3 Rearrangements

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 02 Nov 2024

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At a glance

  • Drugs Digoxin (Primary) ; Metformin (Primary) ; Repotrectinib (Primary) ; Rosuvastatin (Primary)
  • Indications CNS cancer; Solid tumours
  • Focus Pharmacokinetics
  • Sponsors Turning Point Therapeutics

    • Most Recent Events

    • 19 Jul 2024 Status changed from recruiting to not yet recruiting.
    • 19 Jul 2023 Planned End Date changed from 1 Nov 2025 to 30 Nov 2025.
    • 19 Jul 2023 Planned primary completion date changed from 1 Jul 2025 to 31 Jul 2025.

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