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A Phase 2, Randomized, Blinded, Placebo-Controlled, Study to Evaluate Safety, Tolerability, Pharmacometrics, and Efficacy of DNTH103 in Adults With Generalized Myasthenia Gravis (MAGIC)

Trial Profile

A Phase 2, Randomized, Blinded, Placebo-Controlled, Study to Evaluate Safety, Tolerability, Pharmacometrics, and Efficacy of DNTH103 in Adults With Generalized Myasthenia Gravis (MAGIC)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 14 Sep 2026

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At a glance

  • Drugs Claseprubart (Primary)
  • Indications Myasthenia gravis
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms MAGIC
  • Sponsors Dianthus Therapeutics

Most Recent Events

  • 08 Jun 2026 Planned End Date changed from 1 Aug 2027 to 1 Oct 2028.
  • 05 May 2026 According to a Dianthus Therapeutics media release, the company announced the successful completion of our end-of-Phase 2 meeting with the FDA in the first quarter of 2026
  • 05 May 2026 According to a Dianthus Therapeutics media release, data from this study were presented at the 2026 American Academy of Neurology (AAN) Annual Meeting.

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