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A Phase 2, Randomized, Blinded, Placebo-Controlled, Study to Evaluate Safety, Tolerability, Pharmacometrics, and Efficacy of DNTH103 in Adults With Generalized Myasthenia Gravis (MAGIC)

Trial Profile

A Phase 2, Randomized, Blinded, Placebo-Controlled, Study to Evaluate Safety, Tolerability, Pharmacometrics, and Efficacy of DNTH103 in Adults With Generalized Myasthenia Gravis (MAGIC)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 26 Nov 2025

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At a glance

  • Drugs Claseprubart (Primary)
  • Indications Myasthenia gravis
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms MAGIC
  • Sponsors Dianthus Therapeutics

Most Recent Events

  • 30 Oct 2025 According to a Dianthus Therapeutics media release, data from this trial presented during the Myasthenia Gravis Foundation of America (MGFA) Scientific Session of the American Association of Neuromuscular and Electromagnetic Medicine (AANEM) Annual Meeting.
  • 30 Oct 2025 Results published in the Dianthus Therapeutics Media Release
  • 02 Oct 2025 According to a Dianthus Therapeutics media release, the results of this Phase 2 MaGic trial of claseprubart in generalized Myasthenia Gravis (gMG) will be presented in an oral presentation at the American Association of Neuromuscular and Electromagnetic Medicine (AANEM) Annual Meeting, taking place October 29 to November 1, 2025 in San Francisco, California.

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