First-in-human, Open-label Phase 1/2 Study to Investigate Safety and Efficacy of SAR445514, an NKcell Engager (NKCE) Targeting B-cell Maturation Antigen (BCMA) in Monotherapy in Participants With Relapsed/Refractory Multiple Myeloma (RRMM) and in Relapsed/Refractory Light-chain Amyloidosis (RRLCA)

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 10 Mar 2025

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At a glance

Drugs IPH 6401 (Primary)
Indications Amyloid light-chain amyloidosis; Multiple myeloma
Focus Adverse reactions; First in man; Therapeutic Use
Sponsors Sanofi

Most Recent Events

06 Mar 2025 Status changed from recruiting to active, no longer recruiting.
04 Nov 2024 Planned End Date changed from 3 Mar 2028 to 7 Apr 2028.
04 Nov 2024 Planned primary completion date changed from 29 Apr 2026 to 21 Mar 2027.

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