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A Phase 3, Multi-Center, Randomized, Double-Blind Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy

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Trial Profile

A Phase 3, Multi-Center, Randomized, Double-Blind Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 17 Jan 2025

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At a glance

  • Drugs Aficamten (Primary)
  • Indications Hypertrophic cardiomyopathy
  • Focus Registrational; Therapeutic Use
  • Acronyms ACACIA-HCM
  • Sponsors Cytokinetics

    • Most Recent Events

    • 13 Jan 2025 According to a Cytokinetics media release, enrollment in this study is expected to complete in 2H 2025.
    • 19 Nov 2024 According to a Cytokinetics media release, company announced that they have entered into a collaboration and license agreement for the exclusive development and commercialization of aficamten in Japan for the treatment of patients with obstructive and non-obstructive hypertrophic cardiomyopathy (HCM), subject to certain reserved development rights of Cytokinetics.
    • 08 Aug 2024 According to a Cytokinetics media release, company expect to continue enrollment in ACACIA-HCM throughout 2024 and complete enrollment in 2025.

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