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A Phase 3, Open-Label, Randomized Study of Perioperative Dostarlimab Monotherapy Versus Standard of Care in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

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Trial Profile

A Phase 3, Open-Label, Randomized Study of Perioperative Dostarlimab Monotherapy Versus Standard of Care in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 13 Mar 2026

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At a glance

  • Drugs Dostarlimab (Primary) ; Capecitabine; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Colon cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms AZUR-2
  • Sponsors GlaxoSmithKline; GlaxoSmithKline Research & Development; GSK

Most Recent Events

  • 03 Mar 2026 According to AnaptysBio media release, the topline data from the trial is anticipated in 2028.
  • 23 Jan 2026 Planned number of patients changed from 811 to 892.
  • 17 Jul 2025 Planned number of patients changed from 711 to 811.

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